Nature Neuroscience - Current issue : November 2008 - Vol 11 No 11
- Three-dimensional object shape representation
- Gene coexpression relationships in human brain
- Phospholipase A2 in Alzheimer disease
Advance online publication
Movement modulates sensory circuits
Article by Lee and colleaguesIn sedated and whisking rats, Lee et al. show that motor cortex activity enhances sensory processing through a cortico-corticothalamic feedback circuit. In whisking rats, however, inhibitory brainstem input to the thalamus was also enhanced, leading to a net suppression of thalamic sensory responses.
Advance online publication
Modeling motor mistakes
Article by Berniker and KordingThe nervous system produces accurate movements by adapting to environmental changes. Berniker and Kording construct a probabilistic model that compensates for motor errors and estimates their sources. If the motor system used such a strategy, it would explain many movement generalization phenomena.
Advance online publication
Accumulating evidence in decision-making
Article by Tosoni and colleaguesIt has been proposed that neurons in the intraparietal cortex gradually accumulate evidence supporting different response options. Here, Tosoni et al. show that this model generalizes to arbitrary stimulus-response associations in humans.
Web focus
Subtle developmental abnormalities may contribute to mental retardation and psychiatric disorders, and indeed brain "development" continues throughout life. In this Web Focus, we present a collection of papers published over the course of the last year, highlighting the latest progress in the field of CNS development.